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Autor:David Shugar

                

Publikacja w czasopi¶mie

1. Fluorescence emission properties of 8-aza analogues of caffeine, theophylline, and related N-alkyl xanthines  [ LINK ]
BIOORGANIC & MEDICINAL CHEMISTRY Tom 17 Nr 6 r. 2009, str. 2585-2591 (Artykuł)
Grzegorz Mędza, Jacek Wierzchowski, Borys Kierdaszuk, David Shugar
2. Role of ionization of the phosphate cosubstrate on phosphorolysis by purine nucleoside phosphorylase (PNP) of bacterial (E. coli) and mammalian (human) origin.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS Tom 37 Nr 2 r. 2008, str. 153-164 (Artykuł)
Anna Modrak-Wójcik, Aneta Kirilenko, David Shugar, Borys Kierdaszuk
3. Experimental (13C NMR) and theoretical (ab initio Molecular Orbital calculations) studies on the prototropic tautomerism of benzotriazole and some derivatives symmetrically substituted on the benzene ring
JOURNAL OF PHYSICAL CHEMISTRY A Tom 111 r. 2007, str. 6501-6509 (Artykuł)
Jarosław Poznański, Andżelika Najda, Maria Bretner, David Shugar
4. Interactions of calf spleen purine nucleoside phosphorylase with Formycin B and its aglycone - spectroscopic and kinetic studies
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS Tom 26 r. 2007, str. 849-854 (Artykuł)
Jacek Wierzchowski, Beata Iwańska, Maria Bzowska, David Shugar
5. Fluorescence emission properties of 8-azaxanthine and its triazolo N-alkyl derivatives in solution: Analysis of excited-state proton transfer, and potential applications in protein/ligand interactions.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY Tom 179 r. 2006, str. 276-282 (Artykuł)
Jacek Wierzchowski, Jerzy Sepioł, D Sulikowski, Borys Kierdaszuk, David Shugar
6. Interactions of calf spleen purine nucleoside phosphorylase with 8-azaguanine, and a bisubstrate analogue inhibitor: implications for the reaction mechanism
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES Tom 59c r. 2004, str. 713-725 (Artykuł)
Jacek Wierzchowski, Maria Bzowska, Katarzyna Breer, David Shugar
7. Xanthine, xanthosine and its nucleotides: solution structures of neutral and ionic forms, and relevance to substrate properties in various enzyme systems and metabolic pathways  [ LINK ]
ACTA BIOCHIMICA POLONICA Tom 51 Nr 2 r. 2004, str. 493-531 (Artykuł)
Ewa Kulikowska, Borys Kierdaszuk, David Shugar
8. Ability of adenosine-2prim(3prim)-deoxy-3prim(2prim)-triphosphates, and related analogues, to replace ATP as phosphate donor for all human, and Drosphila melanogaster, deoxyribonucleoside kinases.
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS Tom 22 r. 2003, str. 1525-1529 (Artykuł)
Krzysztof Krawiec, Borys Kierdaszuk, Elena Kalinichenko, Elena Rubinova, Igor Mikhailopulo, Staffan Eriksson, Birgitte Munch-Petersen, David Shugar
9. Halogenated benzimidazoles and benzotriazoles as inhibitors of the NTPase/helicase activities of hepatitis C and related viruses
EUROPEAN JOURNAL OF BIOCHEMISTRY Tom 270 r. 2003, str. 1645-1653 (Artykuł)
Peter Borowski, Johanna Deinert, Sarah Schalinski, Maria Bretner, Krzysztof Ginalski, Tadeusz Kulikowski, David Shugar
10. Inorganic tripolyphosphate (PPPi) as a phosphate donor for human deoxyribonucleoside kinases.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Tom 301 r. 2003, str. 192-197 (Artykuł)
Krzysztof Krawiec, Borys Kierdaszuk, David Shugar
11. Striking ability of adenosine-2prim(3prim)-deoxy-3prim(2prim)-triphosphates, and related analogues to replace ATP as phosphate donor for all four human, and the Drosophila melanogaster, deoxyribonucleoside kinases.
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS Tom 22 r. 2003, str. 153-173 (Artykuł)
Borys Kierdaszuk, Krzysztof Krawiec, Elena Kalinichenko, Elena Rubinova, Igor Mikhailopulo, Staffan Eriksson, Birgitte Munch-Petersen, David Shugar
12. Structural Properties of the Neutral and Monoanionic Forms of Xanthosine, Highly Relevant to Their Substrate Properties with Various Enzyme Systems.
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS Tom 22 r. 2003, str. 249-263 (Artykuł)
Jarosław Poznański, Borys Kierdaszuk, David Shugar
13. DFT calculations and parametrization of the approximate Valence Bond method to describe the phosphoryl transfer reaction in a model system
INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY Tom 90 r. 2002, str. 1129-1139 (Artykuł)
Krzysztof Ginalski, Paweł Grochowski, Bogdan Lesyng, David Shugar
14. Purine nucleoside phosphorylase from Cellulomonas sp.: physicochemical properties and binding of substrates determined by ligand-dependent enhancement of enzyme intrinsic fluorescence, and by protective effects of ligands on thermal inactivation.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY Tom 1597 r. 2002, str. 320-334 (Artykuł)
Beata Wielgus-Kutrowska, Maria Bzowska, Jan Tebbe, Gertraud Koellner, David Shugar
15. Selective fluorescent and fluorogenic substrates for purine-nucleoside phosphorylases from various sources, and direct fluorimetric determination of enzyme levels in human and animal blood
ANALYTICA CHIMICA ACTA Tom 472 r. 2002, str. 63-74 (Artykuł)
Jacek Wierzchowski, Maria Ogiela, Beata Iwańska, David Shugar
16. Xanthosine and xanthine. Substrate properties with purine nucleoside phosphorylases, and relevance to other enzyme systems
EUROPEAN JOURNAL OF BIOCHEMISTRY Tom 269 Nr 16 r. 2002, str. 4048-4057 (Artykuł)
Gerasim Stoychev, Borys Kierdaszuk, David Shugar
17. Calf spleen purine nucleoside phosphorylase: structure of its ternary complex with an N(7)-acycloguanosine inhibitor and a phosphate anion
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY Tom D57 r. 2001, str. 30-36 (Artykuł)
Marija Luic, Gertraud Koellner, David Shugar, Wolfram Saenger, Maria Bzowska
18. Interaction of E. coli purine nucleoside phosphorylase (PNP) with the cationic and zwitterionic forms of the fluorescent substrate N(7)-methylguanosine
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY Tom 1544 r. 2001, str. 74-88 (Artykuł)
Gerasim Stoychev, Borys Kierdaszuk, David Shugar
19. Formycin A and its N-methyl analogues, specific inhibitors of E. coli purine nucleoside phosphorylase (PNP): induced tautomeric shifts on binding to enzyme, and enzyme-ligand fluorescence resonance energy transfer.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY Tom 1476 r. 2000, str. 109-128 (Artykuł)
Borys Kierdaszuk, Anna Modrak-Wójcik, Jacek Wierzchowski, David Shugar
20. Purine nucleoside phosphorylase: properties, functions and clinical aspects
PHARMACOLOGY & THERAPEUTICS Tom 88 r. 2000, str. 1-76 (Artykuł)
Maria Bzowska, Ewa Kulikowska, David Shugar
21. Binding of substrates by purine nucleoside phosphorylase (PNP) from Cellulomonas sp. - kinetic and spectrofluorimetric studies
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS Tom 18 r. 1999, str. 871-872 (Artykuł)
Beata Wielgus-Kutrowska, Jan Tebbe, Jacek Wierzchowski, David Shugar, Wolfram Saenger, Gertraud Koellner, Maria Bzowska
22. Crystal structures of purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implications of the molecular mechanism of trimeric PNPs
JOURNAL OF MOLECULAR BIOLOGY Tom 294 r. 1999, str. 1239-1255 (Artykuł)
Jan Tebbe, Maria Bzowska, Beata Wielgus-Kutrowska, Werner Schroder, Zygmunt Kazimierczuk, David Shugar, Wolfram Saenger, Gertraud Koellner
23. Interactions of purine nucleoside phosphorylase with antiviral acyclic nucleoside phosphonate inhibitors - kinetic and emission studies
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS Tom 18 r. 1999, str. 875-876 (Artykuł)
Jacek Wierzchowski, Ewa Kulikowska, Maria Bzowska, Alexander Holy, Lucyna Magnowska, David Shugar
24. Substrate/inhibitor specificities of human deoxycytidine kinase (dCK) and thymidine kinase (TK1 and TK2) towards the sugar moiety of nucleosides, including O(prim)-alkyl analogue"s
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS Tom 18 r. 1999, str. 1883-1903 (Artykuł)
Borys Kierdaszuk, Krzysztof Krawiec, Zygmunt Kazimierczuk, Ulla Jacobsson, Nils Johansson, Birgitte Munch-Petersen, Staffan Eriksson, David Shugar
25. Substrate/inhibitor specificities of human deoxycytidine kinase (dCK) and thymidine kinase (TK1 and TK2) towards the sugar moiety of nucleosides, including Oprim-alkyl analogues.
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS Tom 18 r. 1999, str. 1883-1903 (Artykuł)
Borys Kierdaszuk, Krzysztof Krawiec, Zygmunt Kazimierczuk, Ulla Jacobsson, Nils Johansson, Birgitte Munch-Petersen, Staffan Eriksson, David Shugar

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