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Autor:Maria Bzowska

                

Publikacja w czasopi¶mie

1. New phosphate binding sites in the crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with phosphate and formycin A
FEBS LETTERS Tom 586 r. 2012, str. 967-971 (Artykuł)
Zoran Stefanic, Marta Narczyk, Goran Mikleu±evic, Beata Wielgus-Kutrowska, Maria Bzowska, Marija Luic
2. Trimeric purine nucleoside phosphorylase: exploring postulated one-third-of-the-sites binding in the transition-state
BIOORGANIC & MEDICINAL CHEMISTRY Tom 20 r. 2012, str. 6758-6769 (Artykuł)
Beata Wielgus-Kutrowska, Katarzyna Breer, Mariko Hashimoto, Sadao Hikishim, Tsutomu Yokomatsu, Alicja Dyzma, Marta Narczyk, Agnieszka Girstun, Krzysztof Staroń, Maria Bzowska
3. Validation of the Catalytic Mechanism of E. coli Purine Nucleoside Phosphorylase by Structural and Kinetic Studies
BIOCHIMIE Tom 93 r. 2011, str. 1610-1622 (Artykuł)
Goran Mikleusevic, Zoran Stefanic, Marta Narczyk, Beata Wielgus-Kutrowska, Maria Bzowska, Marija Luic
4. 1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Tom 391 r. 2010, str. 703-708 (Artykuł)
Grzegorz Chojnowski, Katarzyna Breer, Marta Narczyk, Beata Wielgus-Kutrowska, Honorata Czapińska, Mariko Hashimoto, Sadao Hikishima, Tsutomu Yokomatsu, Agnieszka Girstun, Krzysztof Staroń, Maria Bzowska
5. 9-Deaeaguanine derivatives connected by a linker to difluoromethylene phosphonic acid are slow-binding picomolar inhibtors of trimeric purine nucleoside phosphporylase
FEBS JOURNAL Tom 277 r. 2010, str. 1747-1760 (Artykuł)
Katarzyna Breer, Ljubica Glavas-Obrovac, Mirjana Suver, Sadao Hikishima, Mariko Hashimoto, Tsutomu Yokomatsu, Beata Wielgus-Kutrowska, Lucyna Magnowska, Maria Bzowska
6. Antiproliferative activity of purine nucleoside phosphorylase multisubstrate analogue inhibitors containing difluoromethylene phosphonic acid against leukemia and lymphoma cells
CHEMICAL BIOLOGY & DRUG DESIGN Tom 75 r. 2010, str. 392-399 (Artykuł)
Ljubica Glavas-Obrovac, Mirjana Suver, Sadao Hikishima, Mariko Hashimoto, Tsutomu Yokomatsu, Lucyna Magnowska, Maria Bzowska
7. Overexpressed proteins may act as mops removing their ligands from the host cells: a case study of calf PNP
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Tom 391 r. 2010, str. 1203-1209 (Artykuł)
Katarzyna Breer, Beata Wielgus-Kutrowska, Agnieszka Girstun, Krzysztof Staroń, Mariko Hashimoto, Sadao Hikishima, Tsutomu Yokomatsu, Maria Bzowska
8. Structural-based design and synthesis of novel 9-deazaguanine derivatives
BIOORGANIC & MEDICINAL CHEMISTRY Tom 18 r. 2010, str. 2275-2284 (Artykuł)
Sadao Hikishima, Mariko Hashimoto, Lucyna Magnowska, Maria Bzowska, Tsutomu Yokomatsu
9. The comparsion of aggregation and folding of enhanced green fluorescent protein (EGFP) by spectroscopic studeis
SPECTROSCOPY Tom 24 r. 2010, str. 343-348 (Artykuł)
Joanna Krasowska, Monika Olasek, Maria Bzowska, Patricia Clark, Beata Wielgus-Kutrowska
10. 9-Deazaguanine and Its Methyl Derivatives: Synthesis, Antitumor Activity in vitro and Effects on Purine Nucleoside Phosphorylase Gene Expression
CROATICA CHEMICA ACTA Tom 81 r. 2008, str. 147-156 (Artykuł)
Mirjana Suver, Biserka Zinic, Tomislav Portada, Maria Bzowska, Ljubica Glavas-Obrovac
11. 9-Deazaguanine derivatives: synthesis and inhibitory properties as multi-substrate analogue inhibitors of mammalian PNPs
NUCLEIC ACIDS SYMPOSIUM SERIES r. 2008, str. 661-662 (Artykuł)
Tomoyuki Yatsu, Mariko Hashimoto, Sadao Hikishima, Lucyna Magnowska, Maria Bzowska, Tsutomu Yokomatsu
12. On the analysis of fluorimetric titration curves of purine nucleoside phosphorylase
NUCLEIC ACIDS SYMPOSIUM SERIES Tom 52 r. 2008, str. 671-672 (Artykuł)
Jan Antosiewicz, Katarzyna Breer, Maria Bzowska, Beata Wielgus-Kutrowska
13. Overexpression, purification and characterization of functional calf purine nucleoside phosphorylase (PNP)
PROTEIN EXPRESSION AND PURIFICATION Tom 61 r. 2008, str. 122-130 (Artykuł)
Katarzyna Breer, Agnieszka Girstun, Beata Wielgus-Kutrowska, Krzysztof Staroń, Maria Bzowska
14. Simple and universal method to determine dissociation constants for enzyme/ligand complexes
NUCLEIC ACIDS SYMPOSIUM SERIES r. 2008, str. 669-670 (Artykuł)
Maria Bzowska, Lucyna Magnowska
15. Thermodynamic studies of interactions of calf spleen PNP with acyclic phosphonate inhibitors
NUCLEIC ACIDS SYMPOSIUM SERIES r. 2008, str. 663-664 (Artykuł)
Katarzyna Breer, Beata Wielgus-Kutrowska, Mariko Hashimoto, Sado Hikishima, Tsutomu Yokomatsu, Roman Szczepanowski, Matthias Bochtler, Agnieszka Girstun, Krzysztof Staroń, Maria Bzowska
16. Cloning, expression, purification and some properties of calf purine nucleoside phosphorylase
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS Tom 26 r. 2007, str. 855-859 (Artykuł)
Katarzyna Breer, Agnieszka Girstun, Beata Wielgus-Kutrowska, Krzysztof Staroń, Maria Bzowska
17. Fluorescence studies of calf spleen purine nucleoside phosphorylase (PNP) complexes with guanine and 9-deazaguanine
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS Tom 26 r. 2007, str. 841-847 (Artykuł)
Katarzyna Breer, Biserka ®inić, Jacek Wierzchowski, Maria Bzowska
18. Folding and unfolding of non-fluorescent mutant of green fluorescent protein
JOURNAL OF PHYSICS-CONDENSED MATTER Tom 19 r. 2007, str. 285223-285223 (Artykuł)
Beata Wielgus-Kutrowska, Marta Narczyk, Anna Buszko, Maria Bzowska, Patricia Clark
19. Inhibitory properties of nucleotides with difluoromethylenephosphonic acid as a phosphate mimic vs calf spleen purine nucleoside phosphorylase and effect of these analogues on the viability of human blood lymphocytes
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS Tom 26 r. 2007, str. 989-993 (Artykuł)
Ljubica Glavas-Obrovac, Mirjana Suver, Sadao Hikishima, Tsutomu Yokomatsu, Maria Bzowska
20. Interactions of calf spleen purine nucleoside phosphorylase with Formycin B and its aglycone - spectroscopic and kinetic studies
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS Tom 26 r. 2007, str. 849-854 (Artykuł)
Jacek Wierzchowski, Beata Iwańska, Maria Bzowska, David Shugar
21. Kinetics of binding of multisubstrate analogue inhibitor (2-amino-9-[2-(phosphonomethoxy)ethyl]-6-sulfanylpurine) with trimeric purine nucleoside phosphorylase
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS Tom 26 r. 2007, str. 969-974 (Artykuł)
Jan Antosiewicz, Beata Wielgus-Kutrowska, Maciej Długosz, Antonin Holý, Maria Bzowska
22. Synthesis and biological evaluation of 9-deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid as multi-substrate analogue inhibitors of PNP
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Tom 17 r. 2007, str. 4173-4177 (Artykuł)
Sado Hikishima, Mariko Hashimoto, Lucyna Magnowska, Maria Bzowska, Tsutomu Yokomatsu
23. Towards the mechanism of trimeric purine nucleoside phosphorylases: stopped-flow studies of binding of multisubstrate analogue inhibitor - 2-amino-9-[2-(phosphonomethoxy)-ethyl]-6-sulfanylpurine
BIOPHYSICAL CHEMISTRY Tom 125 r. 2007, str. 260-268 (Artykuł)
Beata Wielgus-Kutrowska, Jan Antosiewicz, Maciej Długosz, Antonin Holy, Maria Bzowska
24. Molecular architecture of E. coli purine nucleoside phosphorylase studied by analytical ultracentrifugation and CD-spectroscopy
PROTEIN SCIENCE Tom 15 r. 2006, str. 1794-1800 (Artykuł)
Anna Modrak-Wójcik, Katarzyna Breer, Vladimir Akoev, Michał Żółkiewski, Maria Bzowska
25. Probing the mechanism of purine nucleoside phosphorylase by steady-state kinetic studies and ligand binding characterization determined by fluorimetric titrations
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY Tom 1764 r. 2006, str. 887-902 (Artykuł)
Beata Wielgus-Kutrowska, Maria Bzowska

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